Searchable abstracts of presentations at key conferences in endocrinology

ea0026p208 | Pituitary | ECE2011

High risk of central adrenal insufficiency in GH deficient long-term survivors of childhood acute lymphoblastic leukaemia

Follin C , Link K , Moell C , Wiebe T , Erfurth E M

Introduction: Acute lymphoblastic leukaemia (ALL) is the most common childhood malignancy and accounts for 25% of all childhood cancer. The survival rate is now 85% which emphasis the importance of long-term treatment complications. ALL patients treated with cranial radiotherapy (CRT) and chemotherapy are particularly at risk for GH deficiency (GHD), but little is known about central adrenal deficiency. Partial ACTH deficiency is often asymptomatic, but it may lead to deleteri...